Heme iron danger3/8/2023 ![]() Optimal situations for the production of harmful free radicals with high With poor calcium diets and high “bad” fats, conditions designed specifically in the laboratory to recreate Orders of magnitude higher than the recommended doses, but also combined This meant not only the intake of red meat quantities up to 3 Meat quantities that far exceeded those recommended by all nutritionalĮxaggerated and unrealistic levels of iron exposure. Studies and even clinical trials used red In practice, the authors have used toxicological protocols as if heme or haemin were “exogenous” active ingredients, whereas in reality they are components of a much more complex matrix, such as food. What emerges from this review is a methodological problem that has never been highlighted before: the non-congruence between the environment, the dosage and the separation of heme iron or haemin as if they were active ingredients. The IARC itself in defining red meat as “probably carcinogenic” only on the basis of 14 cohort studies, had already admitted the limits of this association in humans: limits that also emerge from the study published in 2018 in the journal “ Food and Chemical Toxicology” in the specific case of heme iron, on which in vitro studies, animal studies and clinical studies to explore the mechanisms of action have been conducted. Iron, red meat and cancer does not exist. ![]() Today, however, thanks to aĬritical review of the studies taken into consideration by the IARC, we finally Theoretically be responsible for the initiation or promotion of colon cancer, mediated through theįormation of nitrosamines and / or lipid oxidation. This endogenous meat compound has however been identified by IARC as a component that could The most assimilable and biologically most useful form to our vital functions compared to non-heme Meat is one of the richest and most reliable Inconsistencies, the association among heme iron, red meat and cancer does not ![]() Studies taken into consideration by the IARC and its many methodological
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